A snotty situation ensues when Melvin Sneedley, an academically-gifted student, turns into the Bionic Booger Boy and must be stopped by George, Harold, and Captain Underpants. By flipping the pages, the reader may view animated illustrations.

General Jackrabbit and his Robo-Rabbits from Jupiter attempt to take over the world on Ricky Ricotta's birthday.

George and Harold hypnotize their principal who, believing he is the superhero Captain Underpants, leads them to the lair of the nefarious Dr. Diaper. They must then defeat his evil robot henchmen.

Ricky Ricotta, his Mighty Robot, cousin Lucy, and some friends set out to save mousekind from Stupid Stinkbugs from Saturn, with a little help from some special gum and taffy.

"George and Harold are behind bars for a crime they didn't commit! But just as they are settling into their new life, they are pulled from prison by a time-traveling tyrant named Tippy Tinkletrousers! Now the boys are taking a trip back in time to the carefree days of kindergarten, when the scariest thing they had to face was not evil mad scientists or alien cafeteria ladies but a sixth-grade bully named Kipper Krupp, the nephew of their clueless...

"The Supa Buddies bamboozled the baddies, but all's not right in the world. Dog Man has a new problem to pound, and he's going to need his entire pack to help him. Will he go barking up the wrong tree?"--Provided by publisher.

"George and Harold have really done it this time--they've created a monster! She's faster, smarter, and more evil than anything the world has seen before--she's Wedgie Woman! With the help of her horrible robots and her horrendous hairdo, Wedgie Woman is on a mission to take over the world, and she'll give a whopping wedgie to anyone who stands in her way--including Captain Underpants."--P. [4] of cover.

Dog Man has been working hard to overcome his bad habits, but when his obsessions turn to fears, he finds himself the target of an all-new supervillain, while Petey the Cat, who was just released from jail, starts a new life with Li'l Petey.

A small mouse and his best friend, a giant flying robot, attempt to save the Earth when an evil Martian monkey and his mechanical creations attack.

"Petey the Cat is out of jail, and he has a brand-new lease on life his Petey's reevaluated what matters most, Li'l Petey is struggling to find the good in the world. Can Petey and Dog Man stop fighting like cats and dogs long enough to put their paws together and work as a team? They need each other now more than ever -- Li'l Petey (and the world) is counting on them!"--Publisher.